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Decylubiquinone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Decylubiquinone图片
CAS NO:55486-00-5
包装与价格:
包装价格(元)
5mg (7.753 mM * 2 mL in Ethanol)电议
10mg (15.506 mM * 2 mL in Ethanol)电议

产品名称
癸基泛醌
产品介绍
Decylubiquinone 是泛醌 (辅酶 Q10) 的类似物。Decylubiquinone 阻止活性氧 (ROS) 的产生以响应谷胱甘肽消耗并抑制线粒体通透性转变的激活。
生物活性

Decylubiquinone is an analog of ubiquinone (coenzyme Q10). Decylubiquinone blocksreactive oxygen species(ROS)production in response to glutathione depletion and inhibits activation of the mitochondrial permeability transition[1].

体外研究
(In Vitro)

Decylubiquinone (dUb; 10 μm for 6 hours) exerts its effects on ROS by either inhibition of ROS production by cytochrome bc1 or that it scavenged ROS produced[1].
Decylubiquinone inhibits both the dichlorofluorescein (DCF) fluorescence increase resulting from H2O2treatment and the DCF fluorescence increase resulting after glutathione (GSH) depletion using diethylmaleate mitochondrially generated ROS)[1].

Cell Viability Assay[1]

Cell Line:HL60 cells transfected with bcl-2 (bcl-2) (HL60 B cells)
Concentration:10 μM
Incubation Time:6 hours
Result:Attenuated the ROS increase in HL60 (B) cells.
分子量

322.44

性状

Liquid

Formula

C19H30O4

CAS 号

55486-00-5

中文名称

癸基泛醌

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Solution, -20°C, 2 years