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Niclosamide-13C6
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Niclosamide-13C6图片
CAS NO:1325808-64-7
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品名称
BAY2353-13C6
产品介绍
Niclosamide-13C6 是 13C6 标记的 Niclosamide。Niclosamide (BAY2353) 是一种口服生物可利用的氯化水杨酰苯胺,具有驱虫和潜在的抗肿瘤活性。 Niclosamide (BAY2353) 可抑制STAT3,在 HeLa 细胞中IC500.25 μM,并在无细胞试验中抑制 DNA 复制。
生物活性

Niclosamide-13C6 is the 13C6 labeled Niclosamide. Niclosamide (BAY2353) is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Niclosamide (BAY2353) inhibitsSTAT3with IC50 of 0.25 μM in HeLa cells and inhibits DNA replication in a cell-free assay.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

分子量

333.08

Formula

C713C6H8Cl2N2O4

CAS 号

1325808-64-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.