CAS NO: | 341-69-5 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | Orphenadrine hydrochloride is an orally active and non-competitiveNMDA receptorantagonist (crosses the blood-brain barrier) with aKiof 6.0 μM. Orphenadrine hydrochloride relieves stiffness, pain and discomfort due to muscle strains, sprains or other injuries. Orphenadrine hydrochloride is also used to relieve tremors associated with parkinson's disease. Orphenadrine citrate has good neuroprotective properties, can be used in studies of neurodegenerative diseases[1][2]. | ||||||||
体外研究 (In Vitro) | Orphenadrine hydrochloride (12 μM; 24.5 h) shows neuroprotective effects on 3-NPA-induced neurotoxicity cerebellar granule cells[1]. Cell Viability Assay[1]
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体内研究 (In Vivo) | Orphenadrine hydrochloride (10, 20, 30 mg/kg; i.p.; once aday for 3 days) reduces 3-NPA-induced mortality in a dose-dependent manner[1].
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Clinical Trial | |||||||||
分子量 | 305.84 | ||||||||
Formula | C18H24ClNO | ||||||||
CAS 号 | 341-69-5 | ||||||||
中文名称 | 盐酸奥芬那君;盐酸邻甲苯海拉明;奥芬那君盐酸盐 | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |