PROTAC BRD9-binding moiety 5

立即咨询

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

893633-37-9

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

PROTAC BRD9-binding moiety 5 是一种选择性BRD9结合剂，IC₅₀为 4.20 μM，可用于合成 PROTACs。PROTAC BRD9-binding moiety 5 对癌细胞具有抗增殖活性。

生物活性

PROTACBRD9-binding moiety 5 is a selectiveBRD9binder with anIC₅₀value of 4.20 μM, can be used for the synthesis ofPROTACs.PROTACBRD9-binding moiety 5 has antiproliferative activity againstcancercells^[1].

IC₅₀& Target^[1]

BRD9

4.2 μM (IC₅₀)

体外研究
(In Vitro)

PROTAC BRD9-binding moiety 5 (compound 7) (0-250 μM; 48h) has antiproliferative activity against Jurkat, MDA-MB-231, A375 and HCT-116^[1].

Cell Proliferation Assay^[1]

Cell Line:	Jurkat, MDA-MB-231, A375 and HCT-116
Concentration:	0-250 μM
Incubation Time:	48h
Result:	Exhibited antiproliferative activity against Jurkat, MDA-MB-231, A375 and HCT-116 with IC₅₀s of 77 ± 7 μM, 125 ± 8 μM, 133 ± 5 μM and 145 ± 3 μM.

分子量

346.39

Formula

C₁₉H₁₈N₆O

CAS 号

893633-37-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.