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PROTAC BRD9-binding moiety 5
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
PROTAC BRD9-binding moiety 5图片
CAS NO:893633-37-9
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
PROTAC BRD9-binding moiety 5 是一种选择性BRD9结合剂,IC50为 4.20 μM,可用于合成 PROTACs。PROTAC BRD9-binding moiety 5 对癌细胞具有抗增殖活性。
生物活性

PROTACBRD9-binding moiety 5 is a selectiveBRD9binder with anIC50value of 4.20 μM, can be used for the synthesis ofPROTACs.PROTACBRD9-binding moiety 5 has antiproliferative activity againstcancercells[1].

IC50& Target[1]

BRD9

4.2 μM (IC50)

体外研究
(In Vitro)

PROTAC BRD9-binding moiety 5 (compound 7) (0-250 μM; 48h) has antiproliferative activity against Jurkat, MDA-MB-231, A375 and HCT-116[1].

Cell Proliferation Assay[1]

Cell Line:Jurkat, MDA-MB-231, A375 and HCT-116
Concentration:0-250 μM
Incubation Time:48h
Result:Exhibited antiproliferative activity against Jurkat, MDA-MB-231, A375 and HCT-116 with IC50s of 77 ± 7 μM, 125 ± 8 μM, 133 ± 5 μM and 145 ± 3 μM.
分子量

346.39

Formula

C19H18N6O

CAS 号

893633-37-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.