CAS NO: | 2816993-09-4 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | Anti-inflammatory agent 33 is a potentp38αinhibitor. Anti-inflammatory agent 33 inhibits NO production. Anti-inflammatory agent 33 inhibits LPS-inducediNOS,COX-2, p-p38α, p-MK2 protein expression. Anti-inflammatory agent 33 shows anti-inflammatory activity[1]. | ||||||||
体外研究 (In Vitro) | Anti-inflammatory agent 33 (compound 8j) (10, 5, 2.5, 1.25, 0.675 μM; 1+24 h) 在 LPS 诱导的 RAW264.7 细胞中显着抑制 NO 的产生,抑制率为93.97%,IC50值为 1.25 μM[1]。 Western Blot Analysis[1]
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体内研究 (In Vivo) | Anti-inflammatory agent 33 (10, 30 mg/kg; once a day for 14 days) 在大鼠体内表现出剂量依赖性的抗炎活性[1]。
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分子量 | 433.44 | ||||||||
Formula | C22H15N3O5S | ||||||||
CAS 号 | 2816993-09-4 | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |