CAS NO: | 1268720-28-0 |
包装: | 25 μg (277.4 μM * 250 μL in Ethanol) |
市场价: | 6150元 |
生物活性 | Maresin 1, produced by human Mφs from endogenous docosahexaenoic acid (DHA) and a specialized proresolving mediator, stimulates intracellular [Ca2+] and secretion. Maresin 1 possesses anti-inflammatory activity[1][2][3]. | ||||||||
体外研究 (In Vitro) | Maresin 1 (MaR1, 300 nM) reduces neutrophil migration and reactive oxygen species production, besides decreasing IL-1b, TNF-a, IL-6, and INF-g production[3]. Cell Viability Assay[3]
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体内研究 (In Vivo) | Maresin 1 (MaR1) dose-dependently inhibits TRPV1 currents in neurons, blocks capsaicin (100 nM)-induced inward currents (IC50=0.49 nM), and reduces both inflammation- and chemotherapy-induced neuropathic pain in mice[2].
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分子量 | 360.49 | ||||||||
性状 | Liquid | ||||||||
Formula | C22H32O4 | ||||||||
CAS 号 | 1268720-28-0 | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Solution, -20°C, 2 years |