hGGPPS-IN-1

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hGGPPS-IN-1

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

1429012-38-3

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

hGGPPS-IN-1 (Compound 18b) 是人类香叶基香叶基焦磷酸合成酶 (hGGPPS) 的有效抑制剂。hGGPPS-IN-1 是 C-2 取代的噻吩并嘧啶基双膦酸盐 (C2-ThP-BPs) 的类似物。hGGPPS-IN-1 可诱导多发性骨髓瘤 (MM) 细胞的靶向选择性凋亡 (apoptosis)，并在体内表现出抗骨髓瘤活性

生物活性	hGGPPS-IN-1 (Compound 18b) is a potent inhibitor of the human geranylgeranyl pyrophosphate synthase (hGGPPS). hGGPPS-IN-1 is an analogue of C-2-substituted thienopyrimidine-based bisphosphonates (C2-ThP-BPs). hGGPPS-IN-1 induces target-selectiveapoptosisof multiple myeloma (MM) cells and exhibits antimyeloma activity in vivo^[1].
分子量	401.27
Formula	C₁₃H₁₃N₃O₆P₂S
CAS 号	1429012-38-3
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.