CAS NO: | 1638667-81-8 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | DETQ is a selective, allosteric and orally activedopamine D1 receptor(Dopamine Receptor) potentiator. In HEK293 cells expressing the human D1 receptor, DETQ increases cAMP with anEC50of 5.8 nM and aKbof 26 nM. DETQ shows ~30-fold less potent at rat and mouse D1 receptors and is inactive at the human D5 receptor[1]. | ||||||||
IC50& Target[1] |
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体内研究 (In Vivo) | DETQ (10 mg/kg;腹腔注射;一次) 改善雄性人源化 D1 受体敲入小鼠的亚慢性 Phencyclidine 诱导的物体识别记忆缺陷并增强皮质乙酰胆碱流出[2]。
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分子量 | 422.34 | ||||||||
Formula | C22H25Cl2NO3 | ||||||||
CAS 号 | 1638667-81-8 | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |