STAT5-IN-2 是一种具有抗白血病作用的 STAT5 抑制剂（EC50：在 K562 和 KU812 细胞中分别为 9 μM 和 5 μM）。

STAT5-IN-2 is an inhibitor of STAT5 with antileukemic effects (EC50s: 9 μM and 5 μM in K562 and KU812 cells, respectively).

STAT5-IN-2 (100 nM-50 μM) inhibits cell growth in KG1a and MV-4-11 cell lines with EC50 values of 2.6 μM and 3.5 μM, respectively. In K562, KU812, KG1a and MV-4-11 cells, STAT5-IN-2 (10 μM) induces apoptosis. In KG1a, MV-4-11 and KU812 cells, STAT5-IN-2 (10 μM) blocks the phosphorylation of STAT5[1].

2111834-61-6

C26H27N3O

397.51

DMSO:90mg/mL (226.4mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years