Androgen synthesis inhibitor
| Cas No. | 426219-53-6 |
| 别名 | TAK 700 (salt); TAK700 (salt) |
| 化学名 | 6-(7-hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide 2,3-dihydroxy-4-oxo-4-(phenylamino)butanoate |
| Canonical SMILES | CNC(C1=CC2=C(C=C(C3(O)CCN4C3=CN=C4)C=C2)C=C1)=O.O=C(C(O)C(O)C(O)=O)NC5=CC=CC=C5 |
| 分子式 | C28H28N4O7 |
| 分子量 | 532.54 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | TAK-700 is an oral, selective, non-steroidal androgen synthesis inhibitor of the 17,20 lyase, which is a key enzyme in the production of steroidal hormones. In preclinical studies, TAK-700 has been shown to bind to and inhibit the enzyme 17,20 lygase in both the testes and adrenal glands. TAK-700 is currently under clinical Phase III studies. |
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