GinseNOSide Rg6 抑制人淋巴瘤JK细胞增殖并诱导其凋亡,在 HepG2 细胞中抑制 TNF-α 诱导的NF-Κb转录活性,IC50为 29.34 μM。
产品描述
Ginsenoside Rg6 inhibits the proliferation and induces apoptosis of human lymphoma JK cells
体外活性
Ginsenoside Rg6 may inhibit the proliferation and induce apoptosis of human lymphoma JK cells through mitochondrial dysfunction and increased Bax expression and decreased Bcl-2 expression. In addition, ginsenoside Rg6 can also inhibit the transcriptional activity of NF-κB induced by TNF-α in SK-Hep1 cells with IC50 of 25uM.
Cas No.
147419-93-0
分子式
C42H70O12
分子量
767
别名
人参皂苷 Rg6;人参皂苷Rg6
储存和溶解度
DMSO:100 mg/mL (130.38 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years