Oleandrin 是夹竹桃属中的一种类固醇，可抑制Na+/K+-ATPase活性，IC50为 620 nM。

1. Oleandrin, the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of BDNF at both the protein and transcriptional levels. 2. Oleandrin are known to inhibit the Na, K-ATPase pump, resulting in a consequent increase in calcium influx in heart muscle. 3. Oleandrin has stronger anti-proliferative activity in undifferentiated CaCO-2 cells (IC50, 8.25 nM) , causes an autophagic cell death and altered ERK phosphorylation in undifferentiated.

465-16-7

C32H48O9

576.727

Neriostene;Folinerin;Foliandrin;欧夹竹桃苷

Ethanol:Soluble
Pyridine, Methanol, etc.:Soluble
DMSO:60 mg/ml (104.04 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years