Physcion是一种从中药大黄中分离的蒽醌，作为 6-磷酸葡萄糖酸脱氢酶的抑制剂，IC50和Kd值分别为 38.5 μM 和 26.0 μM。它具有通便、保肝、抗炎、抗菌、抗增殖、抗肿瘤作用。

Physcion (Parietin) is an anthraquinone isolated from traditional Chinese medicine Radix et Rhizoma Rhei, acts as an inhibitor of 6-phosphogluconate dehydrogenase, with an IC50 and a Kd of 38.5 μM and 26.0 μM, respectively. Physcion (Parietin) exhibits laxative, hepatoprotective, anti-inflammatory, anti-microbial, anti-proliferative and anti-tumor effects.

Physcion可改变防御相关基因的表达,并使大麦叶中叶子特有的硫素表达增强,从而控制白粉病。

521-61-9

C16H12O5

284.267

大黄素甲醚;Parietin;Physcione;Rheochrysidin

H2O:Insoluble
DMSO:Insoluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years