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5-Geranoxy-7-methoxycoumarin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
5-Geranoxy-7-methoxycoumarin图片
CAS NO:7380-39-4
包装与价格:
包装价格(元)
10 mg电议
1 mL*10 mM(in DMSO)电议

产品介绍
5-Geranoxy-7-methoxycoumarin 是一种香豆素。它诱导细胞凋亡,具有抗癌、抗真菌和抗菌活性。

产品描述

5-Geranoxy-7-methoxycoumarin shows antifungal activity.

体外活性

Two mechanisms of the resistance of citrus fruits against pathogens-preformed and induced antifungal materials-were investigated. METHODS AND RESULTS: Flavedo tissue of lemon contains the following preformed antifungal materials: citral, limettin, 5-Geranoxy-7-methoxycoumarin, and isopimpinellin, which act as the first line of defense against pathogens. Exogenous application of citral to Penicillium-inoculated lemon fruit prevented development of decay. Being subjected to fungal challenge and/or abiotic stress, citrus fruits are elicited to produce the phytoalexin scoparone, considered as another line of fruit defense. According to median effective dose (ED50) of the inhibition of germ-tube elongation or percent germination, scoparone had higher fungitoxicity against Penicillium digitatum Sacc. than the preformed antifungal materials. Different citrus species (lemon, orange, grapefruit, lime, kumquat) varied in their capacities to produce scoparone responding to the combined Penicillium inoculation and heat treatment or to UV illumination. UV illumination of lemon fruit reduced its susceptibility to P. digitatum. CONCLUSIONS: Expression of this effect was directly related to the level of scoparone in illuminated fruit. UV light and citral application were visibly injurious to the flavedo tissues in high dose.

Cas No.

7380-39-4

分子式

C20H24O4

分子量

328.4

储存和溶解度

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years