DeslaNOSide 是一种快速作用的强心苷,可抑制Na-K-ATPase膜泵,导致细胞内钠和钙浓度增加。它用于研究充血性心力衰竭和因折返机制引起的室上性心律失常,并在研究慢性心房颤动时控制心室率。
产品描述
Deslanoside is a rapidly acting cardiac glycoside used to treat congestive heart failure and supraventricular arrhythmias due to reentry mechanisms. Deslanoside inhibits the Na-K-ATPase membrane pump, resulting in an increase in intracellular sodium and calcium concentrations.
体外活性
Deslanoside increases forearm blood flow and cardiac index and decreased heart rate concomitant with a marked decrease in skeletal muscle sympathetic nerve activity [1]. Deslanoside is a metabolite of Lanatoside C [3].
Cas No.
17598-65-1
分子式
C47H74O19
分子量
943.09
别名
Desacetyllanatoside C;去乙酰西地兰;洋地黄;Deacetyllanatoside C
储存和溶解度
DMSO:95mg/mL (100.73 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years