Adibendan是一种选择性的PDE3抑制剂,IC50为2.0 μmol/l。
产品描述
Adibendan is a selective inhibitor of PDE3 with an IC50 of 2.0 μM.
体外活性
Adibendan exerted a concentration-dependent (0.03 –300 μM) positive inotropic effect in papillary muscles (EC50 = 1.3 μM) which was only partially reversible. The IC50 values for the inhibition of PDE1 or PDE2 were more than 60-fold higher[1].
Cas No.
100510-33-6
分子式
C16H14N4O
分子量
278.31
别名
阿地本旦;Adibendanum
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years