RO8994是一种高效且特异性的螺吲哚酮小分子 Mdm2 抑制剂，MTT 增殖试验和HTRF 结合试验的IC50 为 20 nM和 5 nM。

RO8994 is a highly effective and specific inhibitor of spiroindolinone small-molecule MDM2, with IC50 of 20 nM (MTT proliferation assays) and 5 nM (HTRF binding assays).

1309684-94-3

C31H31Cl2FN4O4

613.51

DMSO:45 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years