TG6-129 是有效的EP2受体选择性拮抗剂，可降低 butapROSt 诱导的 P388D1 巨噬细胞中炎症因子的表达。

TG6-129 is an antagonist of the EP2 receptor. TG6-129 suppresses PGE2-induced elevation of cAMP in cells expressing EP2 with an IC50 value of 1.6 μM. TG6-129 reduces the expression of COX-2, IL-1β, IL-6, IL-12, IL-23 and TNF-α induced by the EP2-selective agonist butaprost in P388D1 macrophages.

1164464-14-5

C20H18FN5O3S3

491.58

TG6 129

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years