THS-044 的结合可稳定 HIF2α PAS-B 折叠状态，kd 为 2 μM，并在内源性和临床环境中调节 HIF2 活性。

THS-044 binding stabilizes the HIF2α PAS-B folded state with a kd of 2 μM and regulates HIF2 activity in endogenous and clinical settings.

62054-67-5

C11H12F3N3O3

291.23

N-Morpholino-2-nitro-4-(trifluoromethyl)aniline;N-[2-Nitro-4-(Trifluoromethyl)phenyl]morpholin-4-Amine

DMSO:1.5 mg/mL (5 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years