Chlorambucil 是一种口服活性的氮芥类双功能烷基化剂,具有抗肿瘤活性,可用于研究淋巴细胞白血病、卵巢癌和乳腺癌以及霍奇金病。
产品描述
Chlorambucil is an orally-active antineoplastic aromatic nitrogen mustard. Chlorambucil alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis.
Cas No.
305-03-3
分子式
C14H19Cl2NO2
分子量
304.21
别名
WR-139013;Chloroambucil;CB-1348;苯丁酸氮芥
储存和溶解度
Ethanol:56 mg/mL (184.1 mM)
H2O:<1 mgml
DMSO:56 mg/mL (184.1 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years