Quinacrine dihydrochloride 是一种具有口服活性的抗疟剂,抑制 NF-Κb 并激活 p53 信号转导,诱导肿瘤细胞发生凋亡,具有抗肿瘤和抗寄生虫活性。
产品描述
Quinacrine Hydrochloride is the dihydrochloride salt of the 9-aminoacridine derivative quinacrine with potential antineoplastic and antiparasitic activities.
Cas No.
69-05-6
分子式
C23H32Cl3N3O
分子量
472.88
别名
Quinacrine 2HCl;Mepacrine dihydrochloride;SN-390;疟疾平;阿的平
储存和溶解度
DMSO:12 mg/mL (25.4 mM)
H2O:49 mg/mL (103.6 mM)
Ethanol:27 mg/mL (57.1 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years