G150 是高选择性h-cGAS抑制剂，IC50值为 10.2 nM，用于抑制 dsDNA 引发的干扰素表达。

G150 inhibited interferon expression triggered by DSDNA with IC50 of 10.2 nM.G150 is an effective and highly selective inhibitor of human cyclic GMP-AMP synthase (H-CGAS).

G150 showed dose-dependent inhibitory activity in THP1 cells with cellular IC50 of 1.96?μM[1].

2369751-30-2

C18H16Cl2N4O2

391.25

DMSO:120 mg/mL (306.71 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years