Aminoguanidine hydrochloride 是一种二胺氧化酶和 NO 合酶抑制剂，通过与 3-脱氧葡萄糖酮相互作用降低晚期糖基化终产物 (AGEs) 的水平，是一种治疗糖尿病肾病的研究药物。
| Cas No. | 1937-19-5 |
| 别名 | 氨基胍盐酸盐; Pimagedine hydrochloride; GER-11; Aminoguanidinium chloride |
| 化学名 | carbonohydrazonic diamide hydrochloride |
| Canonical SMILES | N/C(N)=N\N.Cl |
| 分子式 | CH6N4.HCl |
| 分子量 | 110.55 |
| 溶解度 | DMF: >5 mg/ml,DMSO: >5.5 mg/ml,Ethanol: >1.6 mg/ml,PBS pH 7.2: >100 mg/ml |
| 储存条件 | Store at RT |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Aminoguanidine hydrochloride is a diamine oxidase and NO synthase inhibitor, reduces levels of advanced glycation end products (AGEs) through interacting with 3-deoxyglucosone, is an investigational drug for the treatment of diabetic nephropathy. |
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