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Cytidine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Cytidine图片
CAS NO:65-46-3
包装与价格:
包装价格(元)
20 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
Cytosine β-D-riboside
Cytosine-1-β-D-ribofuranoside
胞苷
产品介绍
Cytidine 是一种嘧啶核苷,由通过 β-N1-糖苷键与核糖结合的胞嘧啶组成。它是尿苷的前体,用于 RNA 合成。

产品描述

Cytidine is a pyrimidine nucleoside comprised of a cytosine bound to ribose via a beta-N1-glycosidic bond. Cytidine is a precursor for uridine. Both cytidine and uridine are utilized in RNA synthesis.

体内活性

D-cycloserine (DCS) facilitates extinction of conditioned freezing to the light CS when no drug pre-exposure has occurred, but pre-exposure to DCS just prior to conditioning disrupted the facilitation of extinction effect in mice. [1] D-cycloserine (DCS) which has a high affinity for the glycine modulatory site in the NMDA receptor complex modulated memory processing in a dose-dependent manner. DCS also facilitates retention in 'senescence-accelerated mice' in which impairment of learning andmemory increases with age. [2] D-cycloserine (DCS) exhibits facilitated extinction of fear but are able to reacquire fear of that conditioned stimulus (CS) in a similar manner as saline-treated control rats. DCS-treated rats exhibits generalized extinction (i.e., they are less fearful of a non-extinguished CS) in comparison to controls. [3] D-cycloserine (DCS), an antimycobacterial agent known to cross the blood-brain barrier, binds with high affinity to this glycine modulatory site, functions as a positive modulator, and facilitates performance of learningtasks in rats. DCS appears to be a potent cognitive enhancer at doses lower than those required for antibacterial activity. [4] D-cycloserine injections (3.25, 15, or 30 mg/kg) before 30 non-reinforced light exposures dose-dependently enhances extinction but does not influence fear-potentiated startle in rats that does not receive extinction training. [5]

Cas No.

65-46-3

分子式

C9H13N3O5

分子量

243.22

别名

Cytosine β-D-riboside;Cytosine-1-β-D-ribofuranoside;胞苷

储存和溶解度

H2O:45 mg/mL (185 mM)
Ethanol:<1 mgml
DMSO:46 mg/mL (189.1 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years