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Sulfadoxine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:2447-57-6
包装与价格:
包装价格(元)
500 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
周效磺胺
Sulphadoxine
磺胺多辛
产品介绍
Sulfadoxine是磺胺类化合物,常与pyrimethamine结合起到抗疟疾作用。它抑制HIV在外周血单核细胞中的复制。

产品描述

Sulfadoxine is a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with bacteriostatic and antimalarial properties.

激酶实验

Competitive binding assays: Cells are harvested from 150-sq cm T-flasks, and cytosol is prepared at a protein concentration of approximately 2 mg/mL in phosphate buffer. Aliquots of this 180,000 ×g supernatant are then incubated with various concentrations of Tamoxifen and 2.5 nM [3H]estradiol for 16 hr at 0-4 ℃. The free steroids are absorbed by dextran-charcoal [l0 μL of 0.5% Dextran C-5% Norite A in TE buffer] for 1 hr at 0 ℃, and aliquots are counted after centrifugation at 800 ×g, 30 min. The relative binding ability of each competitor is taken as the ratio of the concentration of radioinert estradiol/competitor required to inhibit one-half of the specific [3H]estradiol binding, with the affinity of estradiol set at 100%.

Cas No.

2447-57-6

分子式

C12H14N4O4S

分子量

310.33

别名

周效磺胺;Sulphadoxine;磺胺多辛

储存和溶解度

DMSO:57 mg/mL (183.7 mM)
Ethanol:<1 mgml
H2O:<1 mgml
Powder: -20°C for 3 years
In solvent: -80°C for 2 years