您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Choline Fenofibrate
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Choline Fenofibrate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:856676-23-8
包装与价格:
包装价格(元)
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
非诺贝特胆碱
Trilipix
ABT-335
产品介绍
Choline Fenofibrate 是 Fenofibric acid 的胆碱盐,在胃肠道中释放游离的 Fenofibric acid。Fenofibric acid 是一种合成的苯氧基异丁酸衍生物和具有抗高血脂活性的前药。

产品描述

Choline Fenofibrate is a choline formulation of fenofibrate, a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic activity.

激酶实验

Cells are harvested, washed, and lysed in NP-40 lysis buffer (50 mM Tris-HCl [pH 7.5], 150 mM NaCl, 0.5% NP-40). Total cell protein is quantified using the Bradford assay and 1-mg/mL protein aliquots are made. Ten microliters of total cell protein is mixed with 290 μL of substrate solution (0.1 mg/mL dithiothreitol [DTT], 0.1 mg/mL albumin, and 1 mM alanine-β-naphthylamide). Fluorometric measurements (340 nm excitation, 400 nm emission) are made after 15 and 30 min. The slope of the line between the 15- and 30-min measurements is used to represent aminopeptidase activity. Total cell protein is preincubated with bestatin, amastatin, puromycin, EDTA, and/or ZnCl2 for 20 min before the fluorometric aminopeptidase assay.

Cas No.

856676-23-8

分子式

C22H28ClNO5

分子量

421.91

别名

非诺贝特胆碱;Trilipix;ABT-335

储存和溶解度

DMSO:6.2 mg/mL),Need ultrasonic and warming
Powder: -20°C for 3 years
In solvent: -80°C for 2 years