Bropirimine 是 toll 样受体 7(TLR7)的合成激动剂，可通过 TLR7 介导 IFN-β 的产生抑制破骨细胞前体细胞向破骨细胞分化。它是一种生物反应调节剂，通过诱导淋巴因子起作用，在膀胱和上尿路的原位移行细胞癌中具有抗癌活性。

Bropirimine (U-54461) is a biological response modifier that is thought to act through the induction of lymphokines.

U-54461.?Bropirimine (U-54461) is a biological response modifier that is thought to act through the induction of lymphokines.?It was originally developed as a potential anticancer agent to be used after tumor debulking through surgery.

56741-95-8

C10H8BrN3O

266.098

U-54461;溴匹立明

DMSO:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years