Telratolimod 是TLR7/8的激动剂,具有抗肿瘤活性。
产品描述
Telratolimod is a toll-like receptors 7/8 agonist. It has an antitumor activity.
体内活性
Telratolimod (50 μg) suppresses the tumor volume and more effectively blocks tumor growth in combination with CpG ODN in BALB/c mice bearing CT26 colon carcinoma cells. Telratolimod (100 μg) plus 200 μg of CpG ODN slows tumor growth and prolongs the survival of mice bearing large tumors [1].
Cas No.
1359993-59-1
分子式
C36H59N5O2
分子量
593.89
别名
MEDI9197;3M-052
储存和溶解度
DMSO:60 mg/mL (101.02 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years