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Norgestrel
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Norgestrel图片
CAS NO:6533-00-2
包装与价格:
包装价格(元)
100 mg电议
200 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
SH-70850
SH-850
FH 122-A
WY-3707
炔诺孕酮
甲基炔诺酮
产品介绍
Norgestrel 是一种孕酮的合成类似物,是一种口服避孕药中常见的化合物,也是一种神经保护性强抗氧化剂,能够防止光诱导的感光细胞中的ROS的生成以及细胞死亡。

产品描述

Norgestrel is a synthetic progestin commonly used alone or in combination with an estrogen for contraception. Norgestrel suppresses the secretion of luteinizing and follicle-stimulating hormones (LH and FSH), thickens cervical mucus, and slows the transit of ova through the fallopian tubes.

激酶实验

F508del-CFTR maturation: Fischer rat thyroid (FRT) cells stably expressing F508del-CFTR are treated with increasing concentrations of VX-809 for 48 hours. After incubation, cells are harvested in ice-cold D-PBS solution (without calcium and magnesium) and pelleted at 1,000 × g at 4 °C. Cell pellets are lysed in 1% Nonidet P-40, 0.5% sodium deoxycholate, 200 mM NaCl, 10 mM Tris, pH 7.8, and 1 mM EDTA plus protease inhibitor mixture (1:250) for 30 minutes on ice. Lysates are spun for 10 minutes at 10,000 × g at 4 °C to pellet nuclei and insoluble material. Approximately 12 μg total protein is heated in Laemmli buffer with 5% β-mercaptoethanol at 37 °C for 5 minutes and loaded onto a 3% to 8% Tris-acetate gel. The gel is transferred to nitrocellulose and processed for Western blotting by using monoclonal CFTR antibody or polyclonal to GAPDH. Blots are developed by enhanced chemiluminescence. Quantification of the relative amounts of bands C and GAPDH is performed by using NIH ImageJ analysis of scanned films.

Cas No.

6533-00-2

分子式

C21H28O2

分子量

624.906

别名

SH-70850;SH-850;FH 122-A;WY-3707;炔诺孕酮;甲基炔诺酮

储存和溶解度

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years