Isodeoxyelephantopin 是从地胆草中分离得到的一种倍半萜烯内酯，能调节LncRNA 的表达，有抗乳腺癌的作用。它可诱导活性氧的生成，抑制NF-Κb 的激活。

Isodeoxyelephantopin can inhibit the growth of various tumor cells.

Isodeoxyelephantopin inhibits the growth of A549 and T47D cells in a dose-dependent and time-dependent manner with IC50 values of 10.46 and 1.3 μg/mL, respectively. Heterodeoxyelephantin showed no significant toxicity to normal lymphocytes. Heterodeoxyelephinin-induced cell death is associated with activated caspase-3 expression, followed by cell cycle stagnation in G2/M phase [1]

38927-54-7

C19H20O6

344.36

异去氧苦地胆苦素;异去氧苦地胆素

DMSO:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years