IRAK4-IN-4 是白介素-1 受体相关激酶抑制剂，IC50为 2.8 nM。它还抑制环 GMP-AM 合酶 ，IC50为 2.1 nM。详细信息请参考专利文献 CN107163044A 中的化合物 15。

IRAK4-IN-4 inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM.IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4) inhibitor, has an IC50 of 2.8 nM.

1850276-58-2

C22H16N2O2

340.37

DMSO:24 mg/mL(70.51 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years