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IFN alpha-IFNAR-IN-1 hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
IFN alpha-IFNAR-IN-1 hydrochloride图片
CAS NO:2070014-98-9
包装与价格:
包装价格(元)
2 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
1 mL*10 mM(in DMSO)电议

产品介绍
IFN alpha-IFNAR-IN-1 hydrochloride 是 IFN-α 和 IFNAR 相互作用的抑制剂。 IFN alpha-IFNAR-IN-1 hydrochloride 抑制 BM-pDCs 的 MVA 诱导的 IFN-α 反应,IC50 为 2-8 μM。

产品描述

IFN alpha-IFNAR-IN-1 hydrochloride is an inhibitor of the interaction between IFN-α and IFNAR. IFN alpha-IFNAR-IN-1 hydrochloride inhibits MVA-induced IFN-α responses by BM-pDCs with IC50 of 2-8 μM.

体外活性

IFN alpha-IFNAR-IN-1 hydrochloride inhibited the IFN-α responses that were elicited after treatment with CpG2216, stimulation with poly(I:C), and infection with VSV-M2, whereas the total IL-12 production was notably less affected under those conditions. IFN alpha-IFNAR-IN-1 hydrochloride specifically inhibits MVA-induced IFN-α responses by BM-pDCs. IFN alpha-IFNAR-IN-1 hydrochloride exerts immunosuppressive activity by the direct interaction with IFN-α[1].

Cas No.

2070014-98-9

分子式

C18H18ClNS

分子量

315.86

储存和溶解度

DMSO:95 mg/mL (300.77 mM),Need ultrasonic
H2O:16 mg/mL (50.66 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years