ML943 是选择性的、口服活性的MALT1 Protease抑制剂。它可抑制 PBMC 或全血中 IL-2 的分泌，PBMC 中抑制的IC50值为 0.07~0.09 μM，全血中抑制的IC50值为 0.6~0.8 μM)。它具有抗炎作用，可用于研究 FcgR 介导的炎症。

MLT-943 is a potent, selective and orally active MALT1 protease inhibitor. [1].

MLT-943 inhibits stimulated-IL-2 secretion in PBMC or in whole blood with a similar?IC50?across species (0.07-0.09 μM in PBMC, 0.6-0.8 μM in whole blood).

1832576-04-1

C16H14ClF3N6O2

414.77

MLT943

DMSO:247 mg/mL (595.51 mM,Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years