Thiethylperazine dimaleate 是 D2 受体和 H1 受体的拮抗剂。 Thiethylperazine dimaleate 是 ABCC1 的激活剂,具有抗菌、止吐和抗精神病作用。
产品描述
Thiethylperazine dimaleate is an antagonist of the D2 receptor and H1 receptor. Thiethylperazine dimaleate is an activator of ABCC1 and possesses antimicrobial, anti-emetic, and antipsychotic effects.
体外活性
Thiethylperazine dimaleate dimaleate is an antagonist of the D2 receptor and H1 receptor. Thiethylperazine dimaleate dimaleate is an activator of ABCC1 and possesses antimicrobial, anti-emetic, and antipsychotic effects[2].
体内活性
In APP/PS1 mice, Thiethylperazine dimaleate (3 mg/kg; intramuscular injection) causes a significant reduction of Aβ42 levels[2].
Cas No.
1179-69-7
分子式
C26H33N3O4S2
分子量
515.69
别名
Norzine;Toresten;Thiethylperazine maleate;二马来酸硫乙基哌嗪
储存和溶解度
DMSO:100 mg/mL (158.3 mM),ultrasonic and warming and heat to 60°C
Powder: -20°C for 3 years
In solvent: -80°C for 2 years