C3a Receptor Agonist结合免疫系统补体途径中的G蛋白偶联C3a受体(C3aRs)。在肠缺血再灌注损伤模型中,C3aR的激活可防止中性粒细胞动员。C3aRs在成年小鼠的神经祖细胞和未成熟神经元上表达。C3a在体外刺激神经祖细胞的分化。
产品描述
C3a Receptor Agonist binds the G protein-coupled C3a receptors (C3aRs) in the immune system complement pathway. Activation of C3aR prevents neutrophils from being mobilized in a model of intestinal ischemia-reperfusion injury. C3aRs are expressed on neural progenitor cells and immature neurons in adult mice. C3a stimulates differentiation of neural progenitor cells in vitro.
Cas No.
944997-60-8
分子式
C27H35N3O2
分子量
433.59
别名
Complement 3a Receptor Agonist;C3a receptor agonist 1;C3a受体激动剂
储存和溶解度
Ethanol:30 mg/mL
DMSO:40mg/mL (92.3mM)
DMF:30 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years