GKT136901 是选择性的和具有口服活性的NADPH氧化酶NOX-1/4抑制剂，Ki分别为 160 和 165 nM。它具有抗炎症活性。它也是一种选择性和直接的过氧亚硝酸清除剂。它可用于糖尿病肾病，中风和神经退行性疾病的研究。

GKT136901 is an inhibitor of NOX1/4.It acts as Selective and Direct Scavenger of Peroxynitrite

GKT136901 is a novel NOX-1/4 inhibitor with potential application in the areas of diabetic nephropathy, stroke, or neurodegeneration[1]

955272-06-7

C19H15ClN4O2

366.81

AK120765

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years