Pleconaril 是一种有潜力研究肠病毒的衣壳抑制剂,， 它可有效抑制复制, IC50值为 50 nM。

Pleconaril is a capsid inhibitor used previously to treat enterovirus infections. Pleconaril is effective in inhibiting replication (IC50: 50 nM).

Pleconaril is a capsid inhibitor designed to dock within a hydrophobic pocket formed by the capsid proteins VP1, VP3 and VP2. Pleconaril leads to stiffening of the capsid structure, preventing RNA release into the cell.

153168-05-9

C18H18F3N3O3

381.355

Picovir;普可那利;VP 63843;Win 63843

DMSO:10 mg/mL,warmed
Powder: -20°C for 3 years
In solvent: -80°C for 2 years