ML604086 是选择性CCR8抑制剂，抑制循环T细胞上 CCL1 与 CCR8 结合，还抑制 CCL1 介导的趋化性并提高细胞内 Ca2 浓度。

ML604086 suppresses CCL1 mediated chemotaxis and enhances intracellular Ca2 concentrations. ML604086 is a selective inhibitor of CCR8. It also inhibiting CCL1 binding to CCR8 on circulating T-cells.

850330-18-6

C27H32N4O4S

508.63

DMSO:105 mg/mL (206.44 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years