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BMS-1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
BMS-1图片
CAS NO:1675201-83-8
包装与价格:
包装价格(元)
2 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
PD1-PDL1 inhibitor 1
PD-1/PD-L1 inhibitor 1
产品介绍
BMS-1是一种PD-1/PD-L1蛋白质/蛋白质相互作用的抑制剂,IC50为 6 到 100 nM。

产品描述

PD1-PD-L1 inhibitor 1 (PD1-PD-L1-IN-1) is an inhibitor of the PD1-PD-L1 protein-protein interaction. It also acts as an immunomodulator. Programmed death ligand 1 (PD-L1) is a protein in humans that is encoded by the CD274 gene and the upregulation of PD-L1 allows Ys to evade the host immune system. High tumor expression of PD-L1 was associated with increased tumor aggressiveness and a 4.5-fold increased risk of death.

Cas No.

1675201-83-8

分子式

C29H33NO5

分子量

475.585

别名

PD1-PDL1 inhibitor 1;PD-1/PD-L1 inhibitor 1

储存和溶解度

DMSO:29 mg/mL (60.98 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years