PROStaglandin E2 是一种激素样物质，参与多种身体功能，如平滑肌的收缩和舒张、血管的扩张和收缩、血压的控制和炎症的调节。

Prostaglandin E2 is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation.

PGE2 exhibits inhibition of IL 2 production in the mixture of irradiated and nonirradiated T lymphocytes. PGE2 (0.1-10 μM) dose-dependently inhibits the production of IL 2. PGE2 acts during the inductive phase of activation of suppressor cells. Preincubation of T lymphocytes with PGE2 induces cells that suppress IL 2 production and PHA proliferation.

PGE2 (0.3 μg/k, i.p.) markedly reduces the number of peritoneab macrophages undergoing phagocytosis of the methacrybate microbeads in rats. PGE2 (0.1 mg/min, i.a.) increases renal blood flow. PGE2 produces a biphasic change in renal vascular resistance, vasodilatation starts at 0.01 mg/min and is maximal at about 3 mg/min, while at the highest dose used (20 mg/min) PGE2 induces renal vasoconstriction.

363-24-6

C20H32O5

352.471

地诺前列酮;前列腺素 E2;Prostaglandin E2 (PGE2);PGE2;Dinoprostone

DMSO:35.3 mg/mL(100 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years