YAP-TEAD-IN-1 acetate 是一种有效的、竞争性的 YAP-TEAD 相互作用抑制剂,IC50 为 25 nM。
产品描述
YAP-TEAD-IN-1 acetate is an effective and competitive inhibitor of YAP–TEAD interaction with an IC50 of 25 nM.
体外活性
YAP-TEAD-IN-1 acetate (2 μM) shows a higher binding affinity to TEAD1 (Kd = 15 nM) than YAP (50-171) (Kd = 40 nM)[1].
Cas No.
TP2160L1
分子式
C95H148ClN23O23S2
分子量
2079.92
别名
YAP-TEAD-IN-1 acetate (1659305-78-8 Free base)
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years