20(S)-Hydroxycholesterol是平滑 (Smo) 癌蛋白的变构激活剂。

20(S)-Hydroxycholesterol is an allosteric activator of the oncoprotein smoothened (Smo).

20(S)-Hydroxycholesterol activates the hedgehog signaling pathway with an EC50 of 3 μM in NIH3T3 cells[2].

516-72-3

C27H46O2

402.65

20α-Hydroxycholesterol

DMSO:27mg/mL (67.1mM),ultrasonic and warming and heat to 60°C
Powder: -20°C for 3 years
In solvent: -80°C for 2 years