Jagged-1 (188-204) TFA(219127-21-6 free base) 是 JAG-1 蛋白的一个片段。 JAG-1 是 Notch 配体,是一种在皮肤中表达最明显的肽。 JAG-1 诱导表皮成熟。将淹没的角质形成细胞单层暴露于钙浓度升高的 JAG-1 会产生具有 loricrin 表达和 NF-alphaB 激活的分层。
产品描述
Jagged-1 (188-204) TFA is a fragment of the JAG-1 protein. JAG-1 is Notch ligand, a peptide that is the most conspicuously expressed ligand in skin. JAG-1 induces epidermal maturation. Exposing submerged keratinocytes monolayers to JAG-1 with elevated calcium concentration produces stratification with loricrin expression and NF-alphaB activation.
Cas No.
TP1293
分子式
C95H128F3N25O28S3
分子量
2221.37
别名
Jagged-1 (188-204) TFA
储存和溶解度
H2O:45mg/ml(20.26mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years