Tauroursodeoxycholic Acid 是一种内质网应激抑制剂。Tauroursodeoxycholate 抑制ERK,显著降低凋亡分子如Caspase-3和Caspase-12表达。
产品描述
Tauroursodeoxycholic acid is the more hydrophilic form of ursodeoxycholic acid, which is the more abundant naturally produced bile acid in humans. Tauroursodeoxycholic acid, on the other hand, is produced abundantly in bears and has been used for centuries as a natural remedy in some Asian countries. Tauroursodeoxycholic acid is being investigated for use in several conditions such as Primary Biliary Cirrhosis (PBC), insulin resistance, amyloidosis, Cystic Fibrosis, Cholestasis, and Amyotrophic Lateral Sclerosis.
Cas No.
14605-22-2
分子式
C26H45NO6S
分子量
499.71
别名
UR 906;TUDCA;Tauroursodeoxycholic Acid;牛磺熊去氧胆酸;Ursodeoxycholyltaurine;Taurolite
储存和溶解度
DMSO:90 mg/mL(180.1 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years