Tacrine hydrochloride hydrate 是一种乙酰胆碱酯酶 (AChE) 和丁酰胆碱酯酶 (BChE) 的抑制剂,它们的IC50值分别为 31 nM 和 25.6 nM。
产品描述
Tacrine hydrochloride hydrate is a cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders.
Cas No.
206658-92-6
分子式
C13H17ClN2O
分子量
252.74
别名
他克林盐酸盐水合物;Tacrine hydrochloride hydrate;Tetrahydroaminoacridine;Tacrine;Tetrahydroaminacrine
储存和溶解度
DMSO:252.2 mM
H2O:252.2 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years