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Amitriptyline
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Amitriptyline图片
CAS NO:50-48-6
包装与价格:
包装价格(元)
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议
500 mg电议

产品介绍
Amitriptyline 是一种具有镇痛特性的三环类抗抑郁药 (TCA)。它广泛用于治疗抑郁症和神经性疼痛。

产品描述

Amitriptyline (MK-230, N-750, Ro41575) is a tricyclic antidepressant (TCA) with analgesic properties. Amitriptyline is widely used to treat depression and neuropathic pain.

体外活性

Amitriptyline inhibits both serotonin transporter (SERT) and norepinephrine transporter (NET) with Ki of 3.45 nM and 13.3 nM, respectively. Amitriptyline is also an inhibitor of histamine receptor H1, histamine receptor H4, 5-HT2 and sigma 1 receptor with Ki of 0.5 nM, 7.31 nM, 235 nM and 287 nM, respectively.

Cas No.

50-48-6

分子式

C20H23N

分子量

277.4

储存和溶解度

H2O:9.7 mg/mL (34.96 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years