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Epiberberine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Epiberberine图片
CAS NO:6873-09-2
包装与价格:
包装价格(元)
10 mg电议
20 mg电议
1 mL*10 mM(in DMSO)电议

产品介绍
Epiberberine 是一种从黄连中得到的生物碱,是AChE和BChE抑制剂,和非竞争性BACE1抑制剂。在 3T3-L1 细胞分化早期,它能够下调 Raf/MEK1/2/ERK1/2 和 AMPKα/Akt 信号通路。它具有抗氧化作用,能够清除 ONOO-,可用于阿尔滋海默症和糖尿病的研究。

产品描述

1. Epiberberine may be caused drug interactions based on CYP2D6 enzyme. 2. Epiberberine has anti-adipogenic effect is mediated by downregulation of the Raf/MEK1/ERK1/2 and AMPKα/Akt pathways during 3T3-L1 adipocyte differentiation. 3. Epiberberine, as the brightest FSA emitter among the alkaloids, can also serve as an efficient conformation probe for HTG DNA and discriminate the DNA G-quadruplex from the RNA counterpart.

Cas No.

6873-09-2

分子式

C20H18NO4

分子量

336.366

储存和溶解度

Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble
DMSO:11 mg/mL(32.7 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years