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Melanotan(MT)-II
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Melanotan(MT)-II图片
CAS NO:121062-08-6
包装与价格:
包装价格(元)
1 mg电议
2 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议

产品名称
美拉诺坦 II
美拉诺坦 (MT)-II
产品介绍
Melanotan (MT)-II 是一种可注射用的多肽荷尔蒙,是合成的黑皮质素受体激动剂,能够促进晒黑。

产品描述

Melanotan (MT)-II, a synthetic melanocortin receptor agonist, is a synthetic analogue of the peptide hormone α-melanocyte-stimulating hormone (α-MSH).

体外活性

Melanotan (MT)-II is a potent non-selective melanocortin receptor agonist with high affinity for MC1, MC3, MC4, and MC5 receptor subtypes which are involved in the regulation of a number of physiological systems, for example, the pigmentary system, energy homoeostasis, sexual functioning, the immune system, inflammation, and the cardiovascular system[1].

体内活性

Melanotan (MT)-II exerts a dose-dependent inducer activity on erection by eliciting erectile events and shortening latency of the first erectile event to occur. Erectile responses elicited by cavernous nerve stimulation are increased after i.v. melanotan (MT)-II (1 mg/kg), thus exerting a facilitator effect on erection[2]. Melanotan (MT)-II promotes peripheral nerve regeneration and has neuroprotective properties in the rat. Melanotan (MT)-II significantly enhances the recovery of sensory function following a crush lesion of the sciatic nerve in the rat at a dose of 20 μg/kg per 48 h, s.c., but not at a dose of 2 or 50 μg/kg[3]. Melanotan (MT)-II is a potent initiator of penile erection in men with erectile dysfunction[4]. Melanotan (MT)-II reduces food intake and body weight and invokes thermogenic responses in a mouse model[5].

Cas No.

121062-08-6

分子式

C50H69N15O9

分子量

1024.18

别名

美拉诺坦 II;美拉诺坦 (MT)-II

储存和溶解度

DMSO:10mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years