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Cyclobenzaprine hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Cyclobenzaprine hydrochloride图片
CAS NO:6202-23-9
包装与价格:
包装价格(元)
500 mg电议
1 g电议
1 mL*10 mM(in DMSO)电议

产品名称
盐酸环苯扎林
Cyclobenzaprine HCl
MK130 hydrochloride
产品介绍
Cyclobenzaprine hydrochloride 是一种具有抗抑郁活性的中枢作用肌肉松弛剂,可减少肌肉痉挛。

产品描述

Cyclobenzaprine Hydrochloride, a centrally acting muscle relaxant with antidepressant activity, leads to a reduction in muscle spasms.

激酶实验

DNA synthesis assay : The rate of DNA synthesis is measured by the incorporation of radioactive thymidine into DNA. HL-60 and KG1a cells are suspended in 2 mL RPMI medium containing 10% fetal serum in 6-well (35 mm diameter) dishes and incubated with different concentrations of corresponding drugs for 48 hours (drugs are added simultaneously). At 48 hours, 0.5 μCi [3H] thymidine (6.7 Ci/mmol) is added to each well and incubated for an additional 24 hours. The cells are placed on GF/C glass fiber filters (2.4 cm diameter), washed with cold 0.9% NaCl, 5% cold trichloroacetic acid and ethanol. The filters containing the DNA are then dried, placed in EcoLite scintillation liquid (ICN) and the radioactivity measured using Beckman LS 6000IC scintillation counter. The IC50 is defined as the concentration of drug that inhibits 50% of the DNA synthesis of the leukemic cell lines from the dose–response curve.

Cas No.

6202-23-9

分子式

C20H22ClN

分子量

311.85

别名

盐酸环苯扎林;Cyclobenzaprine HCl;MK130 hydrochloride

储存和溶解度

DMSO:58 mg/mL (186 mM)
Ethanol:58 mg/mL (186 mM)
H2O:57 mg/mL (182.8 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years