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Auraptene
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Auraptene图片
CAS NO:495-02-3
包装与价格:
包装价格(元)
20 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
7-geranyloxycoumarin
橙皮油内酯
橙皮油素
产品介绍
AuraPTENe 是一种最丰富的天然香叶氧基香豆素。它能够抑制基质金属蛋白酶 2 以及关键炎症因子,包括 IL-6,IL-8 和趋化因子 (C-C 基序) 配体-5 (CCL5)的分泌。

产品描述

Auraptene is a coumarin derived from citrus plants that bears a geranyloxyl moiety at its C-7. It has anti-inflammatory, anti-carcinogenic, anti-bacterial, neuroprotective, and hepatoprotective activities. It inhibits leukocyte activation and induces phase II enzymes during the initiation phase of carcinogenesis.1 When examined for its potential use in Alzheimer's disease treatment, auraptene was shown to inhibit β-secretase (BACE1) activity with an IC50 value of 345.1 μM.

Cas No.

495-02-3

分子式

C19H22O3

分子量

298.382

别名

7-geranyloxycoumarin;橙皮油内酯;橙皮油素

储存和溶解度

DMSO:>20 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years